HDAC3_HUMAN   O15379


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UniProt:O15379

Recommended name:Histone deacetylase 3

EC number:EC:3.5.1.98

Alternative names:(HD3) (RPD3-2) (SMAP45)

Cleaved into:

GeneID:8841

Gene names  (primary ):HDAC3

Gene names  (synonym ):

Gene names  (ORF ):

Length:428

Mass:48848

Sequence:MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDNDKESDVEI

Tissue specificity:Widely expressed.

Induction:Up-regulated by disturbed flow in umbilical vein endothelial cells in vitro (PubMed:25190803).

Developmental stage:

Protein families:Histone deacetylase family, HD type 1 subfamily


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