HERP1_HUMAN Q15011
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UniProt:Q15011
Recommended name:Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
EC number:
Alternative names:(Methyl methanesulfonate(MMF)-inducible fragment protein 1)
Cleaved into:
GeneID:9709
Gene names (primary ):HERPUD1
Gene names (synonym ):HERP KIAA0025 MIF1
Gene names (ORF ):
Length:391
Mass:43720
Sequence:MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN
Tissue specificity:Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.
Induction:Up-regulated by endoplasmic reticulum stress and CREB3. {ECO:0000269|PubMed:10922362, ECO:0000269|PubMed:16940180}.
Developmental stage:
Protein families: