HERP1_HUMAN   Q15011


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UniProt:Q15011

Recommended name:Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

EC number:

Alternative names:(Methyl methanesulfonate(MMF)-inducible fragment protein 1)

Cleaved into:

GeneID:9709

Gene names  (primary ):HERPUD1

Gene names  (synonym ):HERP KIAA0025 MIF1

Gene names  (ORF ):

Length:391

Mass:43720

Sequence:MESETEPEPVTLLVKSPNQRHRDLELSGDRGWSVGHLKAHLSRVYPERPRPEDQRLIYSGKLLLDHQCLRDLLPKQEKRHVLHLVCNVKSPSKMPEINAKVAESTEEPAGSNRGQYPEDSSSDGLRQREVLRNLSSPGWENISRPEAAQQAFQGLGPGFSGYTPYGWLQLSWFQQIYARQYYMQYLAATAASGAFVPPPSAQEIPVVSAPAPAPIHNQFPAENQPANQNAAPQVVVNPGANQNLRMNAQGGPIVEEDDEINRDWLDWTYSAATFSVFLSILYFYSSLSRFLMVMGATVVMYLHHVGWFPFRPRPVQNFPNDGPPPDVVNQDPNNNLQEGTDPETEDPNHLPPDRDVLDGEQTSPSFMSTAWLVFKTFFASLLPEGPPAIAN

Tissue specificity:Widely expressed; in the brain, expression seems to be restricted to neurons and vascular smooth muscle cells. Present in activated microglia in senile plaques in the brain of patients with Alzheimer disease.

Induction:Up-regulated by endoplasmic reticulum stress and CREB3. {ECO:0000269|PubMed:10922362, ECO:0000269|PubMed:16940180}.

Developmental stage:

Protein families:


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