TRI52_HUMAN Q96A61
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UniProt:Q96A61
Recommended name:E3 ubiquitin-protein ligase TRIM52
EC number:EC:2.3.2.27
Alternative names:(RING finger protein 102) (Tripartite motif-containing protein 52)
Cleaved into:
GeneID:84851
Gene names (primary ):TRIM52
Gene names (synonym ):RNF102
Gene names (ORF ):
Length:297
Mass:34653
Sequence:MAGYATTPSPMQTLQEEAVCAICLDYFKDPVSISCGHNFCRGCVTQLWSKEDEEDQNEEEDEWEEEEDEEAVGAMDGWDGSIREVLYRGNADEELFQDQDDDELWLGDSGITNWDNVDYMWDEEEEEEEEDQDYYLGGLRPDLRIDVYREEEILEAYDEDEDEELYPDIHPPPSLPLPGQFTCPQCRKSFTRRSFRPNLQLANMVQIIRQMCPTPYRGNRSNDQGMCFKHQEALKLFCEVDKEAICVVCRESRSHKQHSVLPLEEVVQEYQEIKLETTLVGILQIEQESIHSKAYNQ
Tissue specificity:
Induction:Up-regulated by Golgi stress-inducing agents such nigericin, trichostatin, tetoposide, campothecin and brefeldin A (PubMed:31133683). Up-regulated by IL1B/interleukin-1 beta and TNFA/TNF-alpha (PubMed:28073078). {ECO:0000269|PubMed:28073078, ECO:0000269|PubMed:31133683}.
Developmental stage:
Protein families:TRIM/RBCC family