ADA_HUMAN   P00813


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UniProt:P00813

Recommended name:Adenosine deaminase

EC number:EC:3.5.4.4

Alternative names:(Adenosine aminohydrolase)

Cleaved into:

GeneID:100

Gene names  (primary ):ADA

Gene names  (synonym ):ADA1

Gene names  (ORF ):

Length:363

Mass:40764

Sequence:MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPDFLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAIDLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIFKSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAGQNL

Tissue specificity:Found in all tissues, occurs in large amounts in T-lymphocytes (PubMed:20959412). Expressed at the time of weaning in gastrointestinal tissues. {ECO:0000269|PubMed:20959412}.

Induction:Up-regulated by hypoxia. {ECO:0000269|PubMed:16670267}.

Developmental stage:

Protein families:Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family


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