PKHN1_HUMAN Q494U1
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UniProt:Q494U1
Recommended name:Pleckstrin homology domain-containing family N member 1
EC number:
Alternative names:(PH domain-containing family N member 1) (Cardiolipin and phosphatidic acid-binding protein)
Cleaved into:
GeneID:84069
Gene names (primary ):PLEKHN1
Gene names (synonym ):CLPABP
Gene names (ORF ):
Length:611
Mass:66409
Sequence:MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPGTDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDRWLYHLEKQTALLGGPRRCHSAPPQRRLTRLRTASGHEPGGSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSRSPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETLSSSHQKCPQLGGPEASGGLVQWI
Tissue specificity:Ubiquitous (PubMed:18191643). Epressed in several cancer cell lines of differing origin (PubMed:29531808). {ECO:0000269|PubMed:18191643, ECO:0000269|PubMed:29531808}.
Induction:Up-regulated by hypoxia. {ECO:0000269|PubMed:29531808}.
Developmental stage:
Protein families: