PKHO1_HUMAN Q53GL0
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UniProt:Q53GL0
Recommended name：Pleckstrin homology domain-containing family O member 1
EC number：
Alternative names：(PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein)
Cleaved into：
GeneID：51177
Gene names (primary )：PLEKHO1
Gene names (synonym )：CKIP1 OC120
Gene names (ORF )：HQ0024c
Length：409
Mass：46237
Sequence：MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
Tissue specificity：Abundantly expressed in skeletal muscle and heart, moderately in kidney, liver, brain and placenta and sparingly in the pancreas and lung. Easily detectable in cell lines such as MOLT-4, HEK293 and Jurkat. {ECO:0000269|PubMed:17197158}.
Induction：Up-regulated by IFNG/IFN-gamma and IL2/interleukin-2 or in C2C12 cells. {ECO:0000269|PubMed:14729969, ECO:0000269|PubMed:17197158}.
Developmental stage：
Protein families：