PD1L2_HUMAN Q9BQ51
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UniProt:Q9BQ51
Recommended name：Programmed cell death 1 ligand 2
EC number：
Alternative names：(PD-1 ligand 2) (PD-L2) (PDCD1 ligand 2) (Programmed death ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD antigen CD273)
Cleaved into：
GeneID：80380
Gene names (primary )：PDCD1LG2
Gene names (synonym )：B7DC CD273 PDCD1L2 PDL2
Gene names (ORF )：
Length：273
Mass：30957
Sequence：MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
Tissue specificity：Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. {ECO:0000269|PubMed:11224527}.
Induction：Up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4/interleukin-4. {ECO:0000269|PubMed:11224527, ECO:0000269|PubMed:11283156}.
Developmental stage：
Protein families：Immunoglobulin superfamily, BTN/MOG family