MIIP_HUMAN Q5JXC2
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UniProt:Q5JXC2
Recommended name：Migration and invasion-inhibitory protein
EC number：
Alternative names：(IGFBP2-binding protein) (Invasion-inhibitory protein 45) (IIp45)
Cleaved into：
GeneID：60672
Gene names (primary )：MIIP
Gene names (synonym )：IIP45
Gene names (ORF )：
Length：388
Mass：42824
Sequence：MVEAEELAQLRLLNLELLRQLWVGQDAVRRSVARAASESSLESSSSYNSETPSTPETSSTSLSTSCPRGRSSVWGPPDACRGDLRDVARSGVASLPPAKCQHQESLGRPRPHSAPSLGTSSLRDPEPSGRLGDPGPQEAQTPRSILAQQSKLSKPRVTFSEESAVPKRSWRLRPYLGYDWIAGSLDTSSSITSQPEAFFSKLQEFRETNKEECICSHPEPQLPGLRESSGSGVEEDHECVYCYRVNRRLFPVPVDPGTPCRLCRTPRDQQGPGTLAQPAHVRVSIPLSILEPPHRYHIHRRKSFDASDTLALPRHCLLGWDIFPPKSEKSSAPRNLDLWSSVSAEAQHQKLSGTSSPFHPASPMQMLPPTPTWSVPQVPRPHVPRQKP
Tissue specificity：Ubiquitous. Isoform 1 is expressed in brain but underexpressed in glioma tissues, at protein level. Isoform 2 is not detected in normal organs, but is expressed in gliomas with increasing levels with glioma progression. On the contrary, at protein level, isoform 2 is not detected in gliomas, suggesting that this isoform is unstable in glioma cells. {ECO:0000269|PubMed:14617774}.
Induction：Up-regulated by IGFBP2. {ECO:0000269|PubMed:16901920}.
Developmental stage：
Protein families：