TNF15_HUMAN O95150
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UniProt:O95150
Recommended name:Tumor necrosis factor ligand superfamily member 15
EC number:
Alternative names:(TNF ligand-related molecule 1) (Vascular endothelial cell growth inhibitor)
Cleaved into:Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form
GeneID:9966
Gene names (primary ):TNFSF15
Gene names (synonym ):TL1 VEGI
Gene names (ORF ):
Length:251
Mass:28087
Sequence:MAEDLGLSFGETASVEMLPEHGSCRPKARSSSARWALTCCLVLLPFLAGLTTYLLVSQLRAQGEACVQFQALKGQEFAPSHQQVYAPLRADGDKPRAHLTVVRQTPTQHFKNQFPALHWEHELGLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSITVVITKVTDSYPEPTQLLMGTKSVCEVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISLVDYTKEDKTFFGAFLL
Tissue specificity:Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. {ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219, ECO:0000269|PubMed:9434163, ECO:0000269|PubMed:9872942}.
Induction:Up-regulated by IL1A/interleukin-1 alpha and TNF. {ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219}.
Developmental stage:
Protein families:Tumor necrosis factor family