PTN2_HUMAN   P17706


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UniProt:P17706

Recommended name:Tyrosine-protein phosphatase non-receptor type 2

EC number:EC:3.1.3.48

Alternative names:(T-cell protein-tyrosine phosphatase) (TCPTP)

Cleaved into:

GeneID:5771

Gene names  (primary ):PTPN2

Gene names  (synonym ):PTPT

Gene names  (ORF ):

Length:415

Mass:48473

Sequence:MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL

Tissue specificity:Ubiquitously expressed. Isoform 2 is probably the major isoform. Isoform 1 is expressed in T-cells and in placenta. {ECO:0000269|PubMed:1731319, ECO:0000269|PubMed:2546150}.

Induction:Up-regulated by IL4/interleukin-4 (at protein level). {ECO:0000269|PubMed:17210636}.

Developmental stage:

Protein families:Protein-tyrosine phosphatase family, Non-receptor class 1 subfamily


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