CREL1_HUMAN   Q96HD1


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UniProt:Q96HD1

Recommended name:Protein disulfide isomerase CRELD1

EC number:EC:5.3.4.1

Alternative names:(Cysteine-rich with EGF-like domain protein 1)

Cleaved into:

GeneID:78987

Gene names  (primary ):CRELD1

Gene names  (synonym ):CIRRIN

Gene names  (ORF ):UNQ188/PRO214

Length:420

Mass:45440

Sequence:MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR

Tissue specificity:Highly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas. {ECO:0000269|PubMed:12137942}.

Induction:Up-regulated by inducers of the unfolded protein response (UPR), including tunicamycin and thapsigargin. {ECO:0000269|PubMed:23027870}.

Developmental stage:

Protein families:CRELD family


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