CREL1_HUMAN Q96HD1
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UniProt:Q96HD1
Recommended name:Protein disulfide isomerase CRELD1
EC number:EC:5.3.4.1
Alternative names:(Cysteine-rich with EGF-like domain protein 1)
Cleaved into:
GeneID:78987
Gene names (primary ):CRELD1
Gene names (synonym ):CIRRIN
Gene names (ORF ):UNQ188/PRO214
Length:420
Mass:45440
Sequence:MAPWPPKGLVPAMLWGLSLFLNLPGPIWLQPSPPPQSSPPPQPHPCHTCRGLVDSFNKGLERTIRDNFGGGNTAWEEENLSKYKDSETRLVEVLEGVCSKSDFECHRLLELSEELVESWWFHKQQEAPDLFQWLCSDSLKLCCPAGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNASHLVCSACFGPCARCSGPEESNCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETEVCPGENKQCENTEGGYRCICAEGYKQMEGICVKEQIPESAGFFSEMTEDELVVLQQMFFGIIICALATLAAKGDLVFTAIFIGAVAAMTGYWLSERSDRVLEGFIKGR
Tissue specificity:Highly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas. {ECO:0000269|PubMed:12137942}.
Induction:Up-regulated by inducers of the unfolded protein response (UPR), including tunicamycin and thapsigargin. {ECO:0000269|PubMed:23027870}.
Developmental stage:
Protein families:CRELD family