ERO1B_HUMAN   Q86YB8


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UniProt:Q86YB8

Recommended name:ERO1-like protein beta

EC number:EC:1.8.4.-

Alternative names:(ERO1-L-beta) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta)

Cleaved into:

GeneID:56605

Gene names  (primary ):ERO1B

Gene names  (synonym ):ERO1LB

Gene names  (ORF ):

Length:467

Mass:53543

Sequence:MSQGVRRAGAGQGVAAAVQLLVTLSFLRSVVEAQVTGVLDDCLCDIDSIDNFNTYKIFPKIKKLQERDYFRYYKVNLKRPCPFWAEDGHCSIKDCHVEPCPESKIPVGIKAGHSNKYLKMANNTKELEDCEQANKLGAINSTLSNQSKEAFIDWARYDDSRDHFCELDDERSPAAQYVDLLLNPERYTGYKGTSAWRVWNSIYEENCFKPRSVYRPLNPLAPSRGEDDGESFYTWLEGLCLEKRVFYKLISGLHASINLHLCANYLLEETWGKPSWGPNIKEFKHRFDPVETKGEGPRRLKNLYFLYLIELRALSKVAPYFERSIVDLYTGNAEEDADTKTLLLNIFQDTKSFPMHFDEKSMFAGDKKGAKSLKEEFRLHFKNISRIMDCVGCDKCRLWGKLQTQGLGTALKILFSEKEIQKLPENSPSKGFQLTRQEIVALLNAFGRLSTSIRDLQNFKVLLQHSR

Tissue specificity:Highly expressed in the digestive tract, including the duodenum and lower digestive tract. In the stomach, highly expressed in enzyme-producing chief cells (at protein level). In the pancreas, expressed in islets of Langerhans and, at lower levels, in enzyme-secreting cells (at protein level). Detected at low level in many other tissues. {ECO:0000269|PubMed:10818100, ECO:0000269|PubMed:16012172}.

Induction:Up-regulated by inducers of the unfolded protein response (UPR). {ECO:0000269|PubMed:10818100, ECO:0000269|PubMed:12752442}.

Developmental stage:

Protein families:EROs family


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