DNSL2_HUMAN Q92874
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UniProt:Q92874
Recommended name：Deoxyribonuclease-1-like 2
EC number：EC:3.1.21.-
Alternative names：(DNase I homolog protein DHP1) (Deoxyribonuclease I-like 2) (DNase I-like 2)
Cleaved into：
GeneID：1775
Gene names (primary )：DNASE1L2
Gene names (synonym )：DHP1 DNAS1L2
Gene names (ORF )：
Length：299
Mass：32853
Sequence：MGGPRALLAALWALEAAGTAALRIGAFNIQSFGDSKVSDPACGSIIAKILAGYDLALVQEVRDPDLSAVSALMEQINSVSEHEYSFVSSQPLGRDQYKEMYLFVYRKDAVSVVDTYLYPDPEDVFSREPFVVKFSAPGTGERAPPLPSRRALTPPPLPAAAQNLVLIPLHAAPHQAVAEIDALYDVYLDVIDKWGTDDMLFLGDFNADCSYVRAQDWAAIRLRSSEVFKWLIPDSADTTVGNSDCAYDRIVACGARLRRSLKPQSATVHDFQEEFGLDQTQALAISDHFPVEVTLKFHR
Tissue specificity：Preferentially expressed in the skin and up-regulated during keratinocytes differentiation. Highly abundant (at protein level) in the stratum granulosum. {ECO:0000269|PubMed:16902420}.
Induction：Up-regulated by inflammatory cytokines. {ECO:0000269|PubMed:15203207}.
Developmental stage：
Protein families：DNase I family