ABC3A_HUMAN P31941
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UniProt:P31941
Recommended name：DNA dC->dU-editing enzyme APOBEC-3A
EC number：EC:3.5.4.38
Alternative names：(A3A) (Phorbolin-1)
Cleaved into：
GeneID：100913187
Gene names (primary )：APOBEC3A
Gene names (synonym )：
Gene names (ORF )：
Length：199
Mass：23012
Sequence：MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
Tissue specificity：Expressed in peripheral leukocytes with higher expression in CD14-positive phagocytic cells. Highly expressed in keratinocytes and in periphery blood monocytes. Also detected in non-lymphoid tissues including lung and adipose tissues. Found at high levels in colorectal adenocarcinoma, Burkitt's lymphoma and chronic myelogenous leukemia. {ECO:0000269|PubMed:11863358, ECO:0000269|PubMed:16527742, ECO:0000269|PubMed:20062055, ECO:0000269|PubMed:20308164}.
Induction：Up-regulated by interferon and CpG single-stranded DNA (at protein level). {ECO:0000269|PubMed:20062055, ECO:0000269|PubMed:20615867}.
Developmental stage：
Protein families：Cytidine and deoxycytidylate deaminase family