DDT4L_HUMAN Q96D03
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UniProt:Q96D03
Recommended name:DNA damage-inducible transcript 4-like protein
EC number:
Alternative names:(HIF-1 responsive protein RTP801-like) (Protein regulated in development and DNA damage response 2) (REDD-2)
Cleaved into:
GeneID:115265
Gene names (primary ):DDIT4L
Gene names (synonym ):REDD2 RTP801L
Gene names (ORF ):
Length:193
Mass:21740
Sequence:MVATGSLSSKNPASISELLDCGYHPESLLSDFDYWDYVVPEPNLNEVIFEESTCQNLVKMLENCLSKSKQTKLGCSKVLVPEKLTQRIAQDVLRLSSTEPCGLRGCVMHVNLEIENVCKKLDRIVCDSSVVPTFELTLVFKQENCSWTSFRDFFFSRGRFSSGFRRTLILSSGFRLVKKKLYSLIGTTVIEGS
Tissue specificity:Up-regulated in atherosclerotic plaques relative to healthy segments of the same artery. {ECO:0000269|PubMed:15308555}.
Induction:Up-regulated by oxidized LDL and hypoxia in macrophages. {ECO:0000269|PubMed:15308555}.
Developmental stage:
Protein families:DDIT4 family