BATF_HUMAN Q16520
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UniProt:Q16520
Recommended name：Basic leucine zipper transcriptional factor ATF-like
EC number：
Alternative names：(B-cell-activating transcription factor) (B-ATF) (SF-HT-activated gene 2 protein) (SFA-2)
Cleaved into：
GeneID：10538
Gene names (primary )：BATF
Gene names (synonym )：
Gene names (ORF )：
Length：125
Mass：14120
Sequence：MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSSPRFQP
Tissue specificity：Expressed at highest levels in lung, and at lower levels in placenta, liver, kidney, spleen, and peripheral blood. Detected in SW480 colorectal cancer cell line and several hematopoietic tumor cell lines, including Raji Burkitt's lymphoma. Strongly expressed in mature B- and T-lymphocytes. Also expressed in moderate levels in lymph node and appendix and at low levels in thymus and bone marrow (PubMed:10777209). {ECO:0000269|PubMed:10777209, ECO:0000269|PubMed:8570175, ECO:0000269|PubMed:8630063}.
Induction：Up-regulated by PDCD1 following infection by HIV-1 virus, leading to inhibit T-cell functions and exhaust T-cells. Up-regulated by Epstein-Barr virus (EBV) protein EBNA2 following infection by EBV. {ECO:0000269|PubMed:12719594, ECO:0000269|PubMed:20890291}.
Developmental stage：
Protein families：BZIP family