KLK14_HUMAN   Q9P0G3


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UniProt:Q9P0G3

Recommended name:Kallikrein-14

EC number:EC:3.4.21.-

Alternative names:(hK14) (Kallikrein-like protein 6) (KLK-L6)

Cleaved into:

GeneID:43847

Gene names  (primary ):KLK14

Gene names  (synonym ):KLKL6

Gene names  (ORF ):

Length:267

Mass:29122

Sequence:MSLRVLGSGTWPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK

Tissue specificity:Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level). {ECO:0000269|PubMed:10969073, ECO:0000269|PubMed:11309303, ECO:0000269|PubMed:11352573, ECO:0000269|PubMed:16456535, ECO:0000269|PubMed:16800737, ECO:0000269|PubMed:17110383}.

Induction:Up-regulated by steroid hormone. {ECO:0000269|PubMed:12645335}.

Developmental stage:

Protein families:Peptidase S1 family, Kallikrein subfamily


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