NUPR1_HUMAN O60356
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UniProt:O60356
Recommended name：Nuclear protein 1
EC number：
Alternative names：(Candidate of metastasis 1) (Protein p8)
Cleaved into：
GeneID：26471
Gene names (primary )：NUPR1
Gene names (synonym )：COM1
Gene names (ORF )：
Length：82
Mass：8873
Sequence：MATFPPATSAPQQPPGPEDEDSSLDESDLYSLAHSYLGGGGRKGRTKREAAANTNRPSPGGHERKLVTKLQNSERKKRGARR
Tissue specificity：Widely expressed, with high levels in liver, pancreas, prostate, ovary, colon, thyroid, spinal cord, trachea and adrenal gland, moderate levels in heart, placenta, lung, skeletal muscle, kidney, testis, small intestine, stomach and lymph node, and low levels in brain, spleen, thymus and bone marrow. Not detected in peripheral blood leukocytes. {ECO:0000269|PubMed:10092851}.
Induction：Up-regulated by stress agents, such as nutrient deprivation (at protein level) (PubMed:22565310). Up-regulation by gamma-irradiation is eventually followed by down-regulation (PubMed:19650074). Expression increases with the tumor aggressiveness. up-regulated by DNA-damaging agent such as doxorubicin (PubMed:18690848). {ECO:0000269|PubMed:18690848, ECO:0000269|PubMed:19650074, ECO:0000269|PubMed:22565310}.
Developmental stage：
Protein families：NUPR family