CLC7A_HUMAN Q9BXN2
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UniProt:Q9BXN2
Recommended name:C-type lectin domain family 7 member A
EC number:
Alternative names:(Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)
Cleaved into:
GeneID:64581
Gene names (primary ):CLEC7A
Gene names (synonym ):BGR CLECSF12 DECTIN1
Gene names (ORF ):UNQ539/PRO1082
Length:247
Mass:27627
Sequence:MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGTMAIWRSNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM
Tissue specificity:Highly expressed in peripheral blood leukocytes and dendritic cells. Detected in spleen, bone marrow, lung, muscle, stomach and placenta. {ECO:0000269|PubMed:11470510, ECO:0000269|PubMed:11491532, ECO:0000269|PubMed:11567029, ECO:0000269|PubMed:11745369, ECO:0000269|PubMed:12423684}.
Induction:Up-regulated during differentiation from monocytes into dendritic cells. {ECO:0000269|PubMed:12423684}.
Developmental stage:
Protein families: