CLC7A_HUMAN   Q9BXN2


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UniProt:Q9BXN2

Recommended name:C-type lectin domain family 7 member A

EC number:

Alternative names:(Beta-glucan receptor) (C-type lectin superfamily member 12) (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (CD antigen CD369)

Cleaved into:

GeneID:64581

Gene names  (primary ):CLEC7A

Gene names  (synonym ):BGR CLECSF12 DECTIN1

Gene names  (ORF ):UNQ539/PRO1082

Length:247

Mass:27627

Sequence:MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVIAVVLGTMAIWRSNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAVKTTGVLSSPCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM

Tissue specificity:Highly expressed in peripheral blood leukocytes and dendritic cells. Detected in spleen, bone marrow, lung, muscle, stomach and placenta. {ECO:0000269|PubMed:11470510, ECO:0000269|PubMed:11491532, ECO:0000269|PubMed:11567029, ECO:0000269|PubMed:11745369, ECO:0000269|PubMed:12423684}.

Induction:Up-regulated during differentiation from monocytes into dendritic cells. {ECO:0000269|PubMed:12423684}.

Developmental stage:

Protein families:


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