CEAM6_HUMAN P40199
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UniProt:P40199
Recommended name:Carcinoembryonic antigen-related cell adhesion molecule 6
EC number:
Alternative names:(Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Cleaved into:
GeneID:4680
Gene names (primary ):CEACAM6
Gene names (synonym ):NCA
Gene names (ORF ):
Length:344
Mass:37195
Sequence:MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAPVLSAVATVGITIGVLARVALI
Tissue specificity:Expressed in neutrophils (PubMed:1378450). Expressed in columnar epithelial and goblet cells of the colon (PubMed:10436421). Expressed in numerous tumor cell lines (at protein level) (PubMed:16204051). {ECO:0000269|PubMed:10436421, ECO:0000269|PubMed:1378450, ECO:0000269|PubMed:16204051}.
Induction:Up-regulated in anoikis-resistant pancreatic adenocarcinoma cells (at protein level). {ECO:0000269|PubMed:14724575}.
Developmental stage:
Protein families:Immunoglobulin superfamily, CEA family