RNAS6_HUMAN Q93091
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UniProt:Q93091
Recommended name：Ribonuclease K6
EC number：EC:3.1.27.-
Alternative names：(RNase K6)
Cleaved into：
GeneID：6039
Gene names (primary )：RNASE6
Gene names (synonym )：RNS6
Gene names (ORF )：
Length：150
Mass：17196
Sequence：MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGINNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVCKNRRHNCHQSSKPVNMTDCRLTSGKYPQCRYSAAAQYKFFIVACDPPQKSDPPYKLVPVHLDSIL
Tissue specificity：Highly expressed in spleen (at protein level) (PubMed:8836175, PubMed:25075772). Has little or no expression in healthy kidneys (at protein level) (PubMed:25075772). Detected in interstitial leukocytes in infected kidneys (at protein level) (PubMed:25075772). Expressed in ureter where it localizes to urothelial and submucosal leukocytes (at protein level) (PubMed:25075772). Strong expression in lung and thymus, and lower expression in heart, placenta, pancreas, liver, brain and skeletal muscle (PubMed:8836175, PubMed:25075772). Also expressed in monocytes and neutrophils (PubMed:8836175). {ECO:0000269|PubMed:25075772, ECO:0000269|PubMed:8836175}.
Induction：Up-regulated in CD14+ monocytes in response to the uropathogenic E.coli strain CFT073. {ECO:0000269|PubMed:25075772}.
Developmental stage：
Protein families：Pancreatic ribonuclease family