B3GN8_HUMAN   Q7Z7M8


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UniProt:Q7Z7M8

Recommended name:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

EC number:EC:2.4.1.-

Alternative names:(BGnT-8) (Beta-1,3-Gn-T8) (Beta-1,3-N-acetylglucosaminyltransferase 8) (Beta3Gn-T8)

Cleaved into:

GeneID:374907

Gene names  (primary ):B3GNT8

Gene names  (synonym ):B3GALT7 BGALT15

Gene names  (ORF ):

Length:397

Mass:43396

Sequence:MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRLLFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC

Tissue specificity:Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines. {ECO:0000269|PubMed:15486459, ECO:0000269|PubMed:15620693}.

Induction:Up-regulated in colon cancer. {ECO:0000269|PubMed:15620693}.

Developmental stage:

Protein families:Glycosyltransferase 31 family


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