B3GN8_HUMAN Q7Z7M8
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UniProt:Q7Z7M8
Recommended name:UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
EC number:EC:2.4.1.-
Alternative names:(BGnT-8) (Beta-1,3-Gn-T8) (Beta-1,3-N-acetylglucosaminyltransferase 8) (Beta3Gn-T8)
Cleaved into:
GeneID:374907
Gene names (primary ):B3GNT8
Gene names (synonym ):B3GALT7 BGALT15
Gene names (ORF ):
Length:397
Mass:43396
Sequence:MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRLLFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
Tissue specificity:Highly expressed in small intestine, pancreas, spleen, bone marrow, lung, throat, and ileum, and weakly in fetal brain, cerebellum, heart, liver, tongue, breast, uteri, and testis. Not detected in colon. Differentially expressed in human tumor cell lines. {ECO:0000269|PubMed:15486459, ECO:0000269|PubMed:15620693}.
Induction:Up-regulated in colon cancer. {ECO:0000269|PubMed:15620693}.
Developmental stage:
Protein families:Glycosyltransferase 31 family