CRLF1_HUMAN   O75462


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UniProt:O75462

Recommended name:Cytokine receptor-like factor 1

EC number:

Alternative names:(Cytokine-like factor 1) (CLF-1) (ZcytoR5)

Cleaved into:

GeneID:9244

Gene names  (primary ):CRLF1

Gene names  (synonym ):

Gene names  (ORF ):UNQ288/PRO327

Length:422

Mass:46302

Sequence:MPAGRRGPAAQSARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGLYWTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAR

Tissue specificity:Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. {ECO:0000269|PubMed:9686600}.

Induction:Up-regulated in fibroblast primary cell cultures under stimulation by IFNG/IFN-gamma, TNF and IL6/interleukin-6. {ECO:0000269|PubMed:9686600}.

Developmental stage:

Protein families:Type I cytokine receptor family, Type 3 subfamily


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