CRLF1_HUMAN O75462
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UniProt:O75462
Recommended name:Cytokine receptor-like factor 1
EC number:
Alternative names:(Cytokine-like factor 1) (CLF-1) (ZcytoR5)
Cleaved into:
GeneID:9244
Gene names (primary ):CRLF1
Gene names (synonym ):
Gene names (ORF ):UNQ288/PRO327
Length:422
Mass:46302
Sequence:MPAGRRGPAAQSARRPPPLLPLLLLLCVLGAPRAGSGAHTAVISPQDPTLLIGSSLLATCSVHGDPPGATAEGLYWTLNGRRLPPELSRVLNASTLALALANLNGSRQRSGDNLVCHARDGSILAGSCLYVGLPPEKPVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLRWYGQDNTCEEYHTVGPHSCHIPKDLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGGLEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSVDWKVVDDVSNQTSCRLAGLKPGTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERPGPGGGACEPRGGEPSSGPVRRELKQFLGWLKKHAYCSNLSFRLYDQWRAWMQKSHKTRNQDEGILPSGRRGTARGPAR
Tissue specificity:Highest levels of expression observed in spleen, thymus, lymph node, appendix, bone marrow, stomach, placenta, heart, thyroid and ovary. Strongly expressed also in fetal lung. {ECO:0000269|PubMed:9686600}.
Induction:Up-regulated in fibroblast primary cell cultures under stimulation by IFNG/IFN-gamma, TNF and IL6/interleukin-6. {ECO:0000269|PubMed:9686600}.
Developmental stage:
Protein families:Type I cytokine receptor family, Type 3 subfamily