ASM3A_HUMAN Q92484
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UniProt:Q92484
Recommended name：Acid sphingomyelinase-like phosphodiesterase 3a
EC number：EC:3.1.4.-
Alternative names：(ASM-like phosphodiesterase 3a)
Cleaved into：
GeneID：10924
Gene names (primary )：SMPDL3A
Gene names (synonym )：ASML3A
Gene names (ORF )：
Length：453
Mass：51260
Sequence：MALVRALVCCLLTAWHCRSGLGLPVAPAGGRNPPPAIGQFWHVTDLHLDPTYHITDDHTKVCASSKGANASNPGPFGDVLCDSPYQLILSAFDFIKNSGQEASFMIWTGDSPPHVPVPELSTDTVINVITNMTTTIQSLFPNLQVFPALGNHDYWPQDQLPVVTSKVYNAVANLWKPWLDEEAISTLRKGGFYSQKVTTNPNLRIISLNTNLYYGPNIMTLNKTDPANQFEWLESTLNNSQQNKEKVYIIAHVPVGYLPSSQNITAMREYYNEKLIDIFQKYSDVIAGQFYGHTHRDSIMVLSDKKGSPVNSLFVAPAVTPVKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLEYILTQTYDIEDLQPESLYGLAKQFTILDSKQFIKYYNYFFVSYDSSVTCDKTCKAFQICAIMNLDNISYADCLKQLYIKHNY
Tissue specificity：Detected in blood serum. Detected in macrophages (at protein level). {ECO:0000269|PubMed:25288789}.
Induction：Up-regulated in macrophages in response to cholesterol accumulation. Up-regulated by cAMP. {ECO:0000269|PubMed:25288789}.
Developmental stage：
Protein families：Acid sphingomyelinase family