SGMR2_HUMAN   Q5BJF2


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UniProt:Q5BJF2

Recommended name:Sigma intracellular receptor 2

EC number:

Alternative names:(Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (Transmembrane protein 97)

Cleaved into:

GeneID:27346

Gene names  (primary ):TMEM97

Gene names  (synonym ):MAC30 S2R

Gene names  (ORF ):

Length:176

Mass:20848

Sequence:MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK

Tissue specificity:Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells (PubMed:23922215). {ECO:0000269|PubMed:15375745, ECO:0000269|PubMed:18070364, ECO:0000269|PubMed:7694637, ECO:0000303|PubMed:23922215}.

Induction:Up-regulated in ovarian surface epithelial (OSE) cells with progesterone. {ECO:0000269|PubMed:18070364}.

Developmental stage:

Protein families:TMEM97/sigma-2 receptor family


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