SGMR2_HUMAN Q5BJF2
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UniProt:Q5BJF2
Recommended name:Sigma intracellular receptor 2
EC number:
Alternative names:(Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (Transmembrane protein 97)
Cleaved into:
GeneID:27346
Gene names (primary ):TMEM97
Gene names (synonym ):MAC30 S2R
Gene names (ORF ):
Length:176
Mass:20848
Sequence:MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
Tissue specificity:Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells (PubMed:23922215). {ECO:0000269|PubMed:15375745, ECO:0000269|PubMed:18070364, ECO:0000269|PubMed:7694637, ECO:0000303|PubMed:23922215}.
Induction:Up-regulated in ovarian surface epithelial (OSE) cells with progesterone. {ECO:0000269|PubMed:18070364}.
Developmental stage:
Protein families:TMEM97/sigma-2 receptor family