DERL3_HUMAN   Q96Q80


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UniProt:Q96Q80

Recommended name:Derlin-3

EC number:

Alternative names:(Degradation in endoplasmic reticulum protein 3) (DERtrin-3) (Der1-like protein 3)

Cleaved into:

GeneID:91319

Gene names  (primary ):DERL3

Gene names  (synonym ):C22orf14 DER3 LLN2

Gene names  (ORF ):

Length:235

Mass:26679

Sequence:MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTNFLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFLGQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLEDVFPNQPGGKRLLQTPGFLKLLLDAPAEDPNYLPLPEEQPGPHLPPPQQ

Tissue specificity:Unlike DERL1 and DERL2, restricted to several tissues. Expressed at high levels in placenta, pancreas, spleen and small intestine. {ECO:0000269|PubMed:16449189}.

Induction:Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded protein response (UPR). {ECO:0000269|PubMed:16449189}.

Developmental stage:

Protein families:Derlin family


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