DERL2_HUMAN Q9GZP9
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UniProt:Q9GZP9
Recommended name:Derlin-2
EC number:
Alternative names:(Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)
Cleaved into:
GeneID:51009
Gene names (primary ):DERL2
Gene names (synonym ):DER2 FLANA
Gene names (ORF ):CGI-101 SBBI53
Length:239
Mass:27567
Sequence:MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
Tissue specificity:Ubiquitous. Overexpressed in various hepatocarcinomas. {ECO:0000269|PubMed:11500051, ECO:0000269|PubMed:16449189}.
Induction:Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded protein response (UPR). {ECO:0000269|PubMed:16449189}.
Developmental stage:
Protein families:Derlin family