DERL2_HUMAN   Q9GZP9


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UniProt:Q9GZP9

Recommended name:Derlin-2

EC number:

Alternative names:(Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)

Cleaved into:

GeneID:51009

Gene names  (primary ):DERL2

Gene names  (synonym ):DER2 FLANA

Gene names  (ORF ):CGI-101 SBBI53

Length:239

Mass:27567

Sequence:MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG

Tissue specificity:Ubiquitous. Overexpressed in various hepatocarcinomas. {ECO:0000269|PubMed:11500051, ECO:0000269|PubMed:16449189}.

Induction:Up-regulated in response to endoplasmic reticulum stress via the ERN1-XBP1 pathway of the unfolded protein response (UPR). {ECO:0000269|PubMed:16449189}.

Developmental stage:

Protein families:Derlin family


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