PDK3_HUMAN Q15120
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UniProt:Q15120
Recommended name：[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
EC number：EC:2.7.11.2
Alternative names：(Pyruvate dehydrogenase kinase isoform 3)
Cleaved into：
GeneID：5165
Gene names (primary )：PDK3
Gene names (synonym )：PDHK3
Gene names (ORF )：
Length：406
Mass：46939
Sequence：MRLFRWLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRNRHNDVVPTMAQGVIEYKEKFGFDPFISTNIQYFLDRFYTNRISFRMLINQHTLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ
Tissue specificity：Expressed in heart, skeletal muscle, spinal cord, as well as fetal and adult brain. {ECO:0000269|PubMed:23297365}.
Induction：Up-regulated in response to hypoxia. Up-regulated in response to fatty acids. Up-regulated by PPARD. {ECO:0000269|PubMed:17669420, ECO:0000269|PubMed:18718909, ECO:0000269|PubMed:20715114}.
Developmental stage：
Protein families：PDK/BCKDK protein kinase family