EFNB1_HUMAN P98172
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UniProt:P98172
Recommended name:Ephrin-B1
EC number:
Alternative names:(EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2)
Cleaved into:Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)
GeneID:1947
Gene names (primary ):EFNB1
Gene names (synonym ):EFL3 EPLG2 LERK2
Gene names (ORF ):
Length:346
Mass:38007
Sequence:MARPGQRWLGKWLVAMVVWALCRLATPLAKNLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRPYEYYKLYLVRPEQAAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGLENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDSDGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKLRKRHRKHTQQRAAALSLSTLASPKGGSGTAGTEPSDIIIPLRTTENNYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV
Tissue specificity:Widely expressed (PubMed:8070404, PubMed:7973638). Detected in both neuronal and non-neuronal tissues (PubMed:8070404, PubMed:7973638). Seems to have particularly strong expression in retina, sciatic nerve, heart and spinal cord (PubMed:7973638). {ECO:0000269|PubMed:7973638, ECO:0000269|PubMed:8070404}.
Induction:Up-regulated in response to TNF. {ECO:0000269|PubMed:8070404}.
Developmental stage:
Protein families:Ephrin family