CP2S1_HUMAN Q96SQ9
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UniProt:Q96SQ9
Recommended name：Cytochrome P450 2S1
EC number：EC:1.14.14.-
Alternative names：(CYPIIS1) (Hydroperoxy icosatetraenoate dehydratase) (Thromboxane-A synthase)
Cleaved into：
GeneID：29785
Gene names (primary )：CYP2S1
Gene names (synonym )：
Gene names (ORF )：UNQ891/PRO1906
Length：504
Mass：55817
Sequence：MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR
Tissue specificity：Expressed at higher levels in extrahepatic tissues including trachea, lung, stomach, small intestine, colon, kidney, breast, placenta and spleen (PubMed:11181079, PubMed:12711469). Expressed in peripheral blood leukocytes (PubMed:11181079). Constitutively expressed in skin (at protein level) (PubMed:12711469). {ECO:0000269|PubMed:11181079, ECO:0000269|PubMed:12711469}.
Induction：Up-regulated in skin upon exposure to ultraviolet radiation or treatment with all-trans retinoic acid (substrate-inducible). {ECO:0000269|PubMed:12711469}.
Developmental stage：
Protein families：Cytochrome P450 family