CBPQ_HUMAN Q9Y646
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UniProt:Q9Y646
Recommended name:Carboxypeptidase Q
EC number:EC:3.4.17.-
Alternative names:(Lysosomal dipeptidase) (Plasma glutamate carboxypeptidase)
Cleaved into:
GeneID:10404
Gene names (primary ):CPQ
Gene names (synonym ):LCH1 PGCP
Gene names (ORF ):
Length:472
Mass:51888
Sequence:MKFLIFAFFGGVHLLSLCSGKAICKNGISKRTFEEIKEEIASCGDVAKAIINLAVYGKAQNRSYERLALLVDTVGPRLSGSKNLEKAIQIMYQNLQQDGLEKVHLEPVRIPHWERGEESAVMLEPRIHKIAILGLGSSIGTPPEGITAEVLVVTSFDELQRRASEARGKIVVYNQPYINYSRTVQYRTQGAVEAAKVGALASLIRSVASFSIYSPHTGIQEYQDGVPKIPTACITVEDAEMMSRMASHGIKIVIQLKMGAKTYPDTDSFNTVAEITGSKYPEQVVLVSGHLDSWDVGQGAMDDGGGAFISWEALSLIKDLGLRPKRTLRLVLWTAEEQGGVGAFQYYQLHKVNISNYSLVMESDAGTFLPTGLQFTGSEKARAIMEEVMSLLQPLNITQVLSHGEGTDINFWIQAGVPGASLLDDLYKYFFFHHSHGDTMTVMDPKQMNVAAAVWAVVSYVVADMEEMLPRS
Tissue specificity:Mainly detected in blood plasma. Abundant in placenta and kidney. Present at low level in muscles, liver and skin fibroblasts. Not detected in brain or white blood cells (at protein level). {ECO:0000269|PubMed:10206990}.
Induction:Up-regulated in the majority of hepatitis C virus-associated hepatocellular carcinoma. {ECO:0000269|PubMed:12591738}.
Developmental stage:
Protein families:Peptidase M28 family