JAML_HUMAN   Q86YT9


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UniProt:Q86YT9

Recommended name:Junctional adhesion molecule-like

EC number:

Alternative names:(Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1)

Cleaved into:

GeneID:120425

Gene names  (primary ):JAML

Gene names  (synonym ):AMICA1

Gene names  (ORF ):UNQ722/PRO1387

Length:394

Mass:44339

Sequence:MFCPLKLILLPVLLDYSLGLNDLNVSPPELTVHVGDSALMGCVFQSTEDKCIFKIDWTLSPGEHAKDEYVLYYYSNLSVPIGRFQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVLHVLPEEPKELMVHVGGLIQMGCVFQSTEVKHVTKVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQSWGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSIHLGNLVFKKTIVLHVSPEEPRTLVTPAALRPLVLGGNQLVIIVGIVCATILLLPVLILIVKKTCGNKSSVNSTVLVKNTKKTNPEIKEKPCHFERCEGEKHIYSPIIVREVIEEEEPSEKSEATYMTMHPVWPSLRSDRNNSLEKKSGGGMPKTQQAF

Tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus. Preferentially expressed by mature leukocytes (at protein level). {ECO:0000269|PubMed:12869515, ECO:0000269|PubMed:18948633, ECO:0000269|PubMed:19064666}.

Induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. {ECO:0000269|PubMed:12869515}.

Developmental stage:

Protein families:Immunoglobulin superfamily


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