KDM8_HUMAN Q8N371
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UniProt:Q8N371
Recommended name：Bifunctional peptidase and arginyl-hydroxylase JMJD5
EC number：EC:1.14.11.-
Alternative names：(JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine(3R)-hydroxylase KDM8)
Cleaved into：
GeneID：79831
Gene names (primary )：KDM8
Gene names (synonym )：JMJD5
Gene names (ORF )：
Length：416
Mass：47270
Sequence：MAGDTHCPAEPLAREGTLWEALRALLPHSKEDLKLDLGEKVERSVVTLLQRATELFYEGRRDECLQSSEVILDYSWEKLNTGTWQDVDKDWRRVYAIGCLLKALCLCQAPEDANTVAAALRVCDMGLLMGAAILGDILLKVAAILQTHLPGKRPARGSLPEQPCTKKARADHGLIPDVKLEKTVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEVGSRYTDEEWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQDISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSPGEILFIPVKYWHYVRALDLSFSVSFWWS
Tissue specificity：Weakly expressed in most cells. Highly expressed in breast cancer cells (PubMed:20457893). Expressed in embryonic stem cells (PubMed:24740926). {ECO:0000269|PubMed:20457893, ECO:0000269|PubMed:24740926}.
Induction：Up-regulated upon starvation, DNA replication stress, UV treatment and by camptothecin and etoposide treatment. {ECO:0000269|PubMed:28982940}.
Developmental stage：
Protein families：