TSPY1_HUMAN   Q01534


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UniProt:Q01534

Recommended name:Testis-specific Y-encoded protein 1

EC number:

Alternative names:(Cancer/testis antigen 78) (CT78)

Cleaved into:

GeneID:100289087

Gene names  (primary ):TSPY1

Gene names  (synonym ):TSPY

Gene names  (ORF ):

Length:308

Mass:35012

Sequence:MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS

Tissue specificity:Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines. {ECO:0000269|PubMed:10747295, ECO:0000269|PubMed:8923009}.

Induction:Up-regulated by androgen in a prostate cancer cell line. {ECO:0000269|PubMed:10747295}.

Developmental stage:Detected in 22-week old testis. {ECO:0000269|PubMed:8923009}.

Protein families:Nucleosome assembly protein (NAP) family


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