TSPY1_HUMAN Q01534
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UniProt:Q01534
Recommended name:Testis-specific Y-encoded protein 1
EC number:
Alternative names:(Cancer/testis antigen 78) (CT78)
Cleaved into:
GeneID:100289087
Gene names (primary ):TSPY1
Gene names (synonym ):TSPY
Gene names (ORF ):
Length:308
Mass:35012
Sequence:MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS
Tissue specificity:Specifically expressed in testicular tissues. Isoform 1 and isoform 2 are expressed in spermatogonia and spermatocytes. Found in early testicular carcinoma in situ, spermatogonial cells in testicular tissues of 46,X,Y female and in prostate cancer cell lines. {ECO:0000269|PubMed:10747295, ECO:0000269|PubMed:8923009}.
Induction:Up-regulated by androgen in a prostate cancer cell line. {ECO:0000269|PubMed:10747295}.
Developmental stage:Detected in 22-week old testis. {ECO:0000269|PubMed:8923009}.
Protein families:Nucleosome assembly protein (NAP) family