RSLBA_HUMAN   Q6T310


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UniProt:Q6T310

Recommended name:Ras-like protein family member 11A

EC number:EC:3.6.5.2

Alternative names:

Cleaved into:

GeneID:387496

Gene names  (primary ):RASL11A

Gene names  (synonym ):

Gene names  (ORF ):

Length:242

Mass:27006

Sequence:MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSALG

Tissue specificity:Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells. {ECO:0000269|PubMed:15033445, ECO:0000269|PubMed:17628721}.

Induction:Down-regulated by TGFB1. {ECO:0000269|PubMed:17628721}.

Developmental stage:Down-regulated during development of THP-1 monocytes into macrophages. {ECO:0000269|PubMed:17628721}.

Protein families:Small GTPase superfamily, Ras family


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