RSLBA_HUMAN Q6T310
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UniProt:Q6T310
Recommended name:Ras-like protein family member 11A
EC number:EC:3.6.5.2
Alternative names:
Cleaved into:
GeneID:387496
Gene names (primary ):RASL11A
Gene names (synonym ):
Gene names (ORF ):
Length:242
Mass:27006
Sequence:MRPLSMSGHFLLAPIPESSSDYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVEGDQLSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAEGFLLVYSITDYDSYLSIRPLYQHIRKVHPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKMHGLSGERRRASIIPRPRSPNMQDLKRRFKQALSPKVKAPSALG
Tissue specificity:Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells. {ECO:0000269|PubMed:15033445, ECO:0000269|PubMed:17628721}.
Induction:Down-regulated by TGFB1. {ECO:0000269|PubMed:17628721}.
Developmental stage:Down-regulated during development of THP-1 monocytes into macrophages. {ECO:0000269|PubMed:17628721}.
Protein families:Small GTPase superfamily, Ras family