CNMD_HUMAN   O75829


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UniProt:O75829

Recommended name:Leukocyte cell-derived chemotaxin 1

EC number:

Alternative names:(Chondromodulin)

Cleaved into:Chondrosurfactant protein (CH-SP); Chondromodulin-1 (Chondromodulin-I) (ChM-I)

GeneID:11061

Gene names  (primary ):CNMD

Gene names  (synonym ):CHMI LECT1 MYETS1

Gene names  (ORF ):

Length:334

Mass:37102

Sequence:MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV

Tissue specificity:Detected in cartilage and cardiac valves (at protein level). Detected in the laminae fibrosa, spongiosa and ventricularis layers of normal cardiac valves (at protein level). Expression is decreased cardiac valves of patients with valvular heart disease (at protein level). Weakly expressed in chondrosarcoma. {ECO:0000269|PubMed:16980969}.

Induction:

Developmental stage:Expressed at 9 weeks in developing cartilagenous bone rudiments.

Protein families:Chondromodulin-1 family


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