CASP9_HUMAN P55211
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UniProt:P55211
Recommended name:Caspase-9
EC number:EC:3.4.22.62
Alternative names:(CASP-9) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6)
Cleaved into:Caspase-9 subunit p35; Caspase-9 subunit p10
GeneID:842
Gene names (primary ):CASP9
Gene names (synonym ):MCH6
Gene names (ORF ):
Length:416
Mass:46281
Sequence:MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS
Tissue specificity:Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. {ECO:0000269|PubMed:16857965}.
Induction:
Developmental stage:Expressed at low levels in fetal heart, at moderate levels in neonate heart, and at high levels in adult heart. {ECO:0000269|PubMed:16857965}.
Protein families:Peptidase C14A family