CASP9_HUMAN   P55211


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UniProt:P55211

Recommended name:Caspase-9

EC number:EC:3.4.22.62

Alternative names:(CASP-9) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6)

Cleaved into:Caspase-9 subunit p35; Caspase-9 subunit p10

GeneID:842

Gene names  (primary ):CASP9

Gene names  (synonym ):MCH6

Gene names  (ORF ):

Length:416

Mass:46281

Sequence:MDEADRRLLRRCRLRLVEELQVDQLWDALLSRELFRPHMIEDIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLEDTGQDMLASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKPEVLRPETPRPVDIGSGGFGDVGALESLRGNADLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTAKKMVLALLELAQQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNGTSCPSLGGKPKLFFIQACGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQLDAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMPGCFNFLRKKLFFKTS

Tissue specificity:Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. {ECO:0000269|PubMed:16857965}.

Induction:

Developmental stage:Expressed at low levels in fetal heart, at moderate levels in neonate heart, and at high levels in adult heart. {ECO:0000269|PubMed:16857965}.

Protein families:Peptidase C14A family


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