FOS_HUMAN   P01100


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UniProt:P01100

Recommended name:Proto-oncogene c-Fos

EC number:

Alternative names:(Cellular oncogene fos) (G0/G1 switch regulatory protein 7)

Cleaved into:

GeneID:2353

Gene names  (primary ):FOS

Gene names  (synonym ):G0S7

Gene names  (ORF ):

Length:380

Mass:40695

Sequence:MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL

Tissue specificity:

Induction:

Developmental stage:Expressed at very low levels in quiescent cells. When cells are stimulated to reenter growth, they undergo 2 waves of expression, the first one peaks 7.5 minutes following FBS induction. At this stage, the protein is localized endoplasmic reticulum. The second wave of expression occurs at about 20 minutes after induction and peaks at 1 hour. At this stage, the protein becomes nuclear. {ECO:0000269|PubMed:17160021}.

Protein families:BZIP family, Fos subfamily


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