IL23A_HUMAN Q9NPF7
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UniProt:Q9NPF7
Recommended name：Interleukin-23 subunit alpha
EC number：
Alternative names：(IL-23 subunit alpha) (IL-23-A) (Interleukin-23 subunit p19) (IL-23p19)
Cleaved into：
GeneID：51561
Gene names (primary )：IL23A
Gene names (synonym )：SGRF
Gene names (ORF )：UNQ2498/PRO5798
Length：189
Mass：20730
Sequence：MLGSRAVMLLLLLPWTAQGRAVPGGSSPAWTQCQQLSQKLCTLAWSAHPLVGHMDLREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSLSPSQPWQRLLLRFKILRSLQAFVAVAARVFAHGAATLSP
Tissue specificity：Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level). {ECO:0000269|PubMed:11114383, ECO:0000269|PubMed:16424222}.
Induction：Up-regulated by a wide array of pathogens and pathogen-products together with self-signals for danger or injury. Up-regulated in psoriatic dermal tissues, in dendritic cells of multiple sclerosis patients and in tumors. {ECO:0000269|PubMed:12421946, ECO:0000269|PubMed:15114670, ECO:0000269|PubMed:15486065, ECO:0000269|PubMed:15731058, ECO:0000269|PubMed:16424222, ECO:0000269|PubMed:16688182, ECO:0000269|PubMed:16751425}.
Developmental stage：Expressed by newborns dendritic cells. {ECO:0000269|PubMed:16342235}.
Protein families：IL-6 superfamily