GLNA_HUMAN P15104
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UniProt:P15104
Recommended name:Glutamine synthetase
EC number:EC:6.3.1.2
Alternative names:(GS) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL)
Cleaved into:
GeneID:2752
Gene names (primary ):GLUL
Gene names (synonym ):GLNS
Gene names (ORF ):
Length:373
Mass:42064
Sequence:MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN
Tissue specificity:Expressed in endothelial cells. {ECO:0000269|PubMed:30158707}.
Induction:By glucocorticoids. Vitamin D and the Wnt signaling pathway inhibit its expression and activity. {ECO:0000269|PubMed:18555765}.
Developmental stage:Expressed during early fetal stages. {ECO:0000269|PubMed:18662667}.
Protein families:Glutamine synthetase family