GLNA_HUMAN   P15104


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UniProt:P15104

Recommended name:Glutamine synthetase

EC number:EC:6.3.1.2

Alternative names:(GS) (Glutamate--ammonia ligase) (Palmitoyltransferase GLUL)

Cleaved into:

GeneID:2752

Gene names  (primary ):GLUL

Gene names  (synonym ):GLNS

Gene names  (ORF ):

Length:373

Mass:42064

Sequence:MTTSASSHLNKGIKQVYMSLPQGEKVQAMYIWIDGTGEGLRCKTRTLDSEPKCVEELPEWNFDGSSTLQSEGSNSDMYLVPAAMFRDPFRKDPNKLVLCEVFKYNRRPAETNLRHTCKRIMDMVSNQHPWFGMEQEYTLMGTDGHPFGWPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNETGDEPFQYKN

Tissue specificity:Expressed in endothelial cells. {ECO:0000269|PubMed:30158707}.

Induction:By glucocorticoids. Vitamin D and the Wnt signaling pathway inhibit its expression and activity. {ECO:0000269|PubMed:18555765}.

Developmental stage:Expressed during early fetal stages. {ECO:0000269|PubMed:18662667}.

Protein families:Glutamine synthetase family


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