KCC1D_HUMAN   Q8IU85


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UniProt:Q8IU85

Recommended name:Calcium/calmodulin-dependent protein kinase type 1D

EC number:EC:2.7.11.17

Alternative names:(CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)

Cleaved into:

GeneID:57118

Gene names  (primary ):CAMK1D

Gene names  (synonym ):CAMKID

Gene names  (ORF ):

Length:385

Mass:42914

Sequence:MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK

Tissue specificity:Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. {ECO:0000269|PubMed:11050006, ECO:0000269|PubMed:12935886, ECO:0000269|PubMed:15840691}.

Induction:Expression increases upon treatment of EC cells with DMSO and retinoic acid. Induced by KCL in PC12 cells. {ECO:0000269|PubMed:16324104}.

Developmental stage:Expressed during hippocampal formation with high expression in the pyramidal cell layers. {ECO:0000269|PubMed:16324104, ECO:0000269|PubMed:17056143}.

Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily


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