KCC1D_HUMAN Q8IU85
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UniProt:Q8IU85
Recommended name:Calcium/calmodulin-dependent protein kinase type 1D
EC number:EC:2.7.11.17
Alternative names:(CaM kinase I delta) (CaM kinase ID) (CaM-KI delta) (CaMKI delta) (CaMKID) (CaMKI-like protein kinase) (CKLiK)
Cleaved into:
GeneID:57118
Gene names (primary ):CAMK1D
Gene names (synonym ):CAMKID
Gene names (ORF ):
Length:385
Mass:42914
Sequence:MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK
Tissue specificity:Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. {ECO:0000269|PubMed:11050006, ECO:0000269|PubMed:12935886, ECO:0000269|PubMed:15840691}.
Induction:Expression increases upon treatment of EC cells with DMSO and retinoic acid. Induced by KCL in PC12 cells. {ECO:0000269|PubMed:16324104}.
Developmental stage:Expressed during hippocampal formation with high expression in the pyramidal cell layers. {ECO:0000269|PubMed:16324104, ECO:0000269|PubMed:17056143}.
Protein families:Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily