TP4A1_HUMAN Q93096
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UniProt:Q93096
Recommended name:Protein tyrosine phosphatase type IVA 1
EC number:EC:3.1.3.48
Alternative names:(PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1)
Cleaved into:
GeneID:7803
Gene names (primary ):PTP4A1
Gene names (synonym ):PRL1 PTPCAAX1
Gene names (ORF ):
Length:173
Mass:19815
Sequence:MARMNRPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFKDSNGHRNNCCIQ
Tissue specificity:Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines. {ECO:0000269|PubMed:10940933, ECO:0000269|PubMed:12235145}.
Induction:Strongly down-regulated upon tetrodotoxin treatment. {ECO:0000269|PubMed:15501285}.
Developmental stage:Expressed in fetal liver. {ECO:0000269|PubMed:10940933}.
Protein families:Protein-tyrosine phosphatase family