PHEX_HUMAN P78562
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UniProt:P78562
Recommended name：Phosphate-regulating neutral endopeptidase PHEX
EC number：EC:3.4.24.-
Alternative names：(Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP)
Cleaved into：
GeneID：5251
Gene names (primary )：PHEX
Gene names (synonym )：PEX
Gene names (ORF )：
Length：749
Mass：86474
Sequence：MEAETGSSVETGKKANRGTRIALVVFVGGTLVLGTILFLVSQGLLSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSCRLW
Tissue specificity：Specifically expressed in ovary (PubMed:9070861). Expressed at low levels in kidney (PubMed:9070861). {ECO:0000269|PubMed:9070861}.
Induction：
Developmental stage：Expressed in fetal lung (PubMed:9070861, PubMed:9077527). Expressed in fetal calvaria and to a lesser extent in fetal kidney and skeletal muscles (PubMed:9593714, PubMed:9077527). {ECO:0000269|PubMed:9070861, ECO:0000269|PubMed:9077527, ECO:0000269|PubMed:9593714}.
Protein families：Peptidase M13 family