FIGLA_HUMAN Q6QHK4
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UniProt:Q6QHK4
Recommended name:Factor in the germline alpha
EC number:
Alternative names:(FIGalpha) (Class C basic helix-loop-helix protein 8) (bHLHc8) (Folliculogenesis-specific basic helix-loop-helix protein) (Transcription factor FIGa)
Cleaved into:
GeneID:344018
Gene names (primary ):FIGLA
Gene names (synonym ):BHLHC8
Gene names (ORF ):
Length:219
Mass:24123
Sequence:MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV
Tissue specificity:Germ cells. Expressed in the fetal ovary, but not by a range of other tissues. Expression increases across mid-gestation, rising some 40-fold by the time of primordial follicle formation. {ECO:0000269|PubMed:12468641, ECO:0000269|PubMed:15044608}.
Induction:
Developmental stage:Expressed in ovarian follicles (from the primordial through to the secondary stage), in mature oocytes, and less frequently in preimplantation embryos. {ECO:0000269|PubMed:12468641}.
Protein families: