EID1_HUMAN Q9Y6B2
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UniProt:Q9Y6B2
Recommended name:EP300-interacting inhibitor of differentiation 1
EC number:
Alternative names:(21 kDa pRb-associated protein) (CREBBP/EP300 inhibitory protein 1) (E1A-like inhibitor of differentiation 1) (EID-1)
Cleaved into:
GeneID:23741
Gene names (primary ):EID1
Gene names (synonym ):C15orf3 CRI1 RBP21
Gene names (ORF ):PNAS-22 PTD014
Length:187
Mass:20876
Sequence:MSEMAELSELYEESSDLQMDVMPGEGDLPQMEVGSGSRELSLRPSRSGAQQLEEEGPMEEEEAQPMAAPEGKRSLANGPNAGEQPGQVAGADFESEDEGEEFDDWEDDYDYPEEEQLSGAGYRVSAALEEADKMFLRTREPALDGGFQMHYEKTPFDQLAFIEELFSLMVVNRLTEELGCDEIIDRE
Tissue specificity:Widely expressed. Most abundantly expressed in heart, skeletal muscle, pancreas, brain and testis. Expressed at much lower levels in placenta and peripheral blood leukocyte. Barely detectable in lung. Also weakly expressed in lung carcinoma A-549 and various leukemia cell lines. {ECO:0000269|PubMed:11073990, ECO:0000269|PubMed:11223246}.
Induction:Down-regulated in differentiating U-937 leukemia cells. {ECO:0000269|PubMed:11073989}.
Developmental stage:Expression decreased with development in ventricular tissue while remaining highly expressed in adult atrial tissue. In primary cultures of human skeletal myocytes, expression decreased during myogenic differentiation (at protein level). {ECO:0000269|PubMed:11073990}.
Protein families: