HCAR2_HUMAN   Q8TDS4


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UniProt:Q8TDS4

Recommended name:Hydroxycarboxylic acid receptor 2

EC number:

Alternative names:(G-protein coupled receptor 109A) (G-protein coupled receptor HM74A) (Niacin receptor 1) (Nicotinic acid receptor)

Cleaved into:

GeneID:338442

Gene names  (primary ):HCAR2

Gene names  (synonym ):GPR109A HCA2 HM74A NIACR1

Gene names  (ORF ):

Length:363

Mass:41850

Sequence:MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP

Tissue specificity:Expression largely restricted to adipose tissue and spleen. Expressed on mature neutrophils but not on immature neutrophils or eosinophils. {ECO:0000269|PubMed:12522134, ECO:0000269|PubMed:17932499}.

Induction:

Developmental stage:Expression in neutrophils occurs in the late terminal differentiation phase. {ECO:0000269|PubMed:17932499}.

Protein families:G-protein coupled receptor 1 family


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