HCAR2_HUMAN Q8TDS4
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UniProt:Q8TDS4
Recommended name:Hydroxycarboxylic acid receptor 2
EC number:
Alternative names:(G-protein coupled receptor 109A) (G-protein coupled receptor HM74A) (Niacin receptor 1) (Nicotinic acid receptor)
Cleaved into:
GeneID:338442
Gene names (primary ):HCAR2
Gene names (synonym ):GPR109A HCA2 HM74A NIACR1
Gene names (ORF ):
Length:363
Mass:41850
Sequence:MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
Tissue specificity:Expression largely restricted to adipose tissue and spleen. Expressed on mature neutrophils but not on immature neutrophils or eosinophils. {ECO:0000269|PubMed:12522134, ECO:0000269|PubMed:17932499}.
Induction:
Developmental stage:Expression in neutrophils occurs in the late terminal differentiation phase. {ECO:0000269|PubMed:17932499}.
Protein families:G-protein coupled receptor 1 family