CCDB1_HUMAN   O95273


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UniProt:O95273

Recommended name:Cyclin-D1-binding protein 1

EC number:

Alternative names:(Grap2 and cyclin-D-interacting protein) (Human homolog of Maid)

Cleaved into:

GeneID:23582

Gene names  (primary ):CCNDBP1

Gene names  (synonym ):DIP1 GCIP HHM

Gene names  (ORF ):

Length:360

Mass:40262

Sequence:MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL

Tissue specificity:Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas. {ECO:0000269|PubMed:10801854, ECO:0000269|PubMed:10854051, ECO:0000269|PubMed:10915743, ECO:0000269|PubMed:15887118, ECO:0000269|PubMed:17131381}.

Induction:Expression is induced by sodium butyrate, an inhibitor of colon cancer cell proliferation. {ECO:0000269|PubMed:17131381}.

Developmental stage:Expression may increase during differentiation. {ECO:0000269|PubMed:10854051}.

Protein families:CCNDBP1 family


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