CCDB1_HUMAN O95273
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UniProt:O95273
Recommended name:Cyclin-D1-binding protein 1
EC number:
Alternative names:(Grap2 and cyclin-D-interacting protein) (Human homolog of Maid)
Cleaved into:
GeneID:23582
Gene names (primary ):CCNDBP1
Gene names (synonym ):DIP1 GCIP HHM
Gene names (ORF ):
Length:360
Mass:40262
Sequence:MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
Tissue specificity:Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas. {ECO:0000269|PubMed:10801854, ECO:0000269|PubMed:10854051, ECO:0000269|PubMed:10915743, ECO:0000269|PubMed:15887118, ECO:0000269|PubMed:17131381}.
Induction:Expression is induced by sodium butyrate, an inhibitor of colon cancer cell proliferation. {ECO:0000269|PubMed:17131381}.
Developmental stage:Expression may increase during differentiation. {ECO:0000269|PubMed:10854051}.
Protein families:CCNDBP1 family