SIX2_HUMAN Q9NPC8
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UniProt:Q9NPC8
Recommended name:Homeobox protein SIX2
EC number:
Alternative names:(Sine oculis homeobox homolog 2)
Cleaved into:
GeneID:10736
Gene names (primary ):SIX2
Gene names (synonym ):
Gene names (ORF ):
Length:291
Mass:32286
Sequence:MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS
Tissue specificity:Strongly expressed in skeletal muscle. Expressed in Wilms' tumor and in the cap mesenchyme of fetal kidney (at protein level). {ECO:0000269|PubMed:22703800}.
Induction:
Developmental stage:Found at 48 dpc in the anterior cranial base with detection concentrated in the sphenoid precursor. Expression is also detected in the pituitary gland. {ECO:0000269|PubMed:20515681}.
Protein families:SIX/Sine oculis homeobox family