REG1A_HUMAN   P05451


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UniProt:P05451

Recommended name:Lithostathine-1-alpha

EC number:

Alternative names:(Islet cells regeneration factor) (ICRF) (Islet of Langerhans regenerating protein) (REG) (Pancreatic stone protein) (PSP) (Pancreatic thread protein) (PTP) (Regenerating islet-derived protein 1-alpha) (REG-1-alpha) (Regenerating protein I alpha)

Cleaved into:

GeneID:5967

Gene names  (primary ):REG1A

Gene names  (synonym ):PSPS PSPS1 REG

Gene names  (ORF ):

Length:166

Mass:18731

Sequence:MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN

Tissue specificity:In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. {ECO:0000269|PubMed:2394826}.

Induction:

Developmental stage:High expression levels in fetal and infant brains; much lower in adult brains. {ECO:0000269|PubMed:2394826}.

Protein families:


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