IBP3_HUMAN P17936
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UniProt:P17936
Recommended name:Insulin-like growth factor-binding protein 3
EC number:
Alternative names:(IBP-3) (IGF-binding protein 3) (IGFBP-3)
Cleaved into:
GeneID:3486
Gene names (primary ):IGFBP3
Gene names (synonym ):IBP3
Gene names (ORF ):
Length:291
Mass:31674
Sequence:MQRARPTLWAAALTLLVLLRGPPVARAGASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVREPGCGCCLTCALSEGQPCGIYTERCGSGLRCQPSPDEARPLQALLDGRGLCVNASAVSRLRAYLLPAPPAPGNASESEEDRSAGSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGYTTKGKEDVHCYSMQSK
Tissue specificity:Expressed by most tissues. Present in plasma.
Induction:Up-regulated in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, EGF and phorbol esters.
Developmental stage:IGFBP3 levels are higher during extrauterine life and peak during puberty.
Protein families: